Natural ingredients are a great place to start, but it’s our scientific approach and Dr. Ferri’s medical insight that drive our results.

The scientific development of all our products is led by Dr. Francesca Ferri. Along with her team of cosmetic scientists at EffegiLab, she brings over 35 years of skincare research and development expertise to our range. As a pioneer in the use of plant extracts in the treatment of dermatological conditions, she was the first to discover the benefit of Mahonia Aquifolium (holly-leaved barberry) in the treatment of psoriasis, and she was the originator of a process to extract Resveratrol from red grapes to treat both psoriasis and dermatitis.

Amongst the formulation breakthroughs that Dr. Ferri has led us to:

Using Myoxinol™ to reduce wrinkles.
Extracted from Hibiscus Esculenta Seeds, Myoxinol™ acts like Botulinum toxin to smooth laughter lines, crow’s feet and frown lines. Myoxinol™ is found in our Hibiscus Night Cream, Hibiscus Serum and Prickly Pear Face Cream.

Using Pistachio Oil to hydrate and help renew the skin.
Omega 3, 6 & 9 Pistachio Oil deeply moisturizes the skin while promoting cellular renewal. It's found in our Pistachio Face Mask, Pistachio Lip Balm, Orange Blossom Face Oil and Orange Blossom Body Oil.

Protecting and moisturizing with Prickly Pear Polysaccharides.
Produced from prickly pear leaves harvested in Sicily, the polysaccharides in our Prickly Pear Face Cream and Prickly Pear Body Cream act like Hyaluronic Acid to hydrate the skin, and also help to reduce skin inflammation.


Our knowledge of the science of skincare makes it possible to formulate products that are both highly effective and gentle on the skin. Each of our 75, or so, active ingredients have been chosen to work in harmony with each other and to complement the body’s natural biochemistry. We look for active ingredients that are already naturally present in the skin or for biomimetic ingredients, which helps to ensure that they are biocompatible and exceptionally skin-friendly. The concentration and combination of ingredients in each formulation are then scientifically optimized to deliver the most benefit while avoiding any harmful side effects.


Science also guides us to strictly limit the use of ‘essential oils’ because they contain potentially irritating allergens like citral, linalool, and farnesol. Avoiding these common sources of irritation in ‘natural’ products is a key objective of our product development process. That’s why our fragrances have been screened to trace levels for all of the 26 fragrance allergens that EU law regards as potentially harmful. All 26 of these allergens are now required by EU law to be flagged on the ingredients panel, but you’ll never find any of them on our list.


All our skincare products undergo standard dermatological tests and have been certified as non-irritant. But because of our focus on the highest standard of skin-friendliness, we also have a clinical program of testing on sensitive skin. In these trials, we maximize the chance of a bad reaction by keeping the product occluded on the skin for 96 hours on people who report that they have healthy but sensitive skin. That’s how we can scientifically claim that our Almond Cleansing Milk, Helichrysum Hyaluronic Toner, Lemon Toner, Pistachio Face Mask, Hibiscus Serum, Rose Face Oil, Prickly Pear Face Cream, Aloe Vera Face Cream and Hibiscus Night Cream are clinically approved for sensitive skin.

Natural Skincare That Shows Results

Our scientific approach to skincare means we conduct clinical trials both to confirm the real world results of our products, and to demonstrate the effectiveness of our novel active ingredients. Understanding the science of Myoxinol™, a novel ‘active’ extracted from Hibiscus seeds, is becoming increasingly important because of the evident appeal of our Myoxinol™ products. Indeed their ability to visibly reduce wrinkles is so pronounced that Myoxinol™ is now being compared to the gold standard of wrinkle reduction - injectable botulinum toxin.

In our clinical trials we’ve shown wrinkle reduction with our Myoxinol™ regime (Prickly Pear Face Cream, Hibiscus Night Cream and Hibiscus Serum) that’s not only clearly visible, but also gets more and more obvious with continued use.

Strong performance in clinical trials often correlates with the popular appeal of a product. Take the Pistachio Face Mask; this very popular and multi-award winning product has been shown in trials to immediately ‘plump’ the skin, and then to deliver significant additional moisturization for over 12 hours, after just one application.